Title: Research Professor
College: Public Health and Health Professions
Department: Environmental and Global Health
Curriculum vitae: PDF
Research Interests: Detection, isolation, and genetic analysis of arboviruses and respiratory viruses (especially animal and human influenza viruses and coronaviruses); Discovery and genetic analyses of viruses associated with fatal infections in farmed cervids; Aerovirology specializing in the collection of airborne viruses; Stability, spread and decontamination of respiratory viruses on environmental surfaces; Polyomavirus regulatory region structure and function; Molecular and classical diagnostic virology (human and animal); Paramyxovirus detection, isolation, and genetic analysis; Development of human and animal virus detection, isolation, and identification methodologies; Determination of whole genomic sequences of DNA and RNA viruses; Diagnostic (clinical) microbiology (bacteriology, mycology, parasitology, and virology); Reverse genetics of RNA viruses: expression of viral genes and virus production.
Hobbies: Cooking and dining, soccer, wildlife viewing, and attending cultural events
Dr. John Lednicky has broad training and experience in microbiology and molecular biology, and performs both basic and applied research. He has worked with various bacteria, fungi, and viruses, some of which are select agents, in a variety of settings that include A/BSL3 laboratories. At the University of Florida, he engages in many multi-disciplinary projects that cover a range in topics, including aerobioogy, virus discovery, and research on the outcomes of inhaled nanoparticles on subsequent respiratory virus infections.
At his previous job at MRIGlobal, first as Principal Scientist, then as Senior Advisor, he managed and provided technical oversight and guidance for programs involving molecular biology, virology, and microbiology; served as a corporate expert in the area of virology and molecular biology; developed and directed research programs; wrote and reviewed research proposals, technical reports, and presentations; and managed technical aspects, schedules, and budgets of programs. While there, he established a ferret model for intranasal and aerosol studies with H5N1 and other influenza viruses.
His recent work includes detection and/or isolation of metapneumoviruses, unusual reassortant influenza A viruses, neurotropic Canine morbillivirus, an arenavirus, human and murine coronaviruses, the genetic characterization of a unique rhinovirus C and of a unique strain of human polyomavirus. The Lednicky laboratory also engineers cells that express specific virus receptors; these cells facilitate the isolation and propagation of the viruses that bind the receptors. Finally, the laboratory also evaluates antivirals (synthetic and natural) in-vitro and has the experience to do so in animal models.
Environmental and Global Health
College of Public Health and Health Professions
101 S. Newel Drive (HPNP Bldg.) Rm 4155
Gainesville, Florida 32610-0188
Office phone: 352-273-9204
Fax: (352) 273-6070
Emerging Pathogens Institute
P.O. Box 100009
Gainesville, Florida 32610-0009
Voice: (352) 273-7526
Fax: (352) 273-9430